Gene interactions and pathways from curated databases and text-mining

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PTGS1 — REN

Text-mined interactions from Literome

Svendsen et al., Eur J Clin Pharmacol 2000 : However, ibuprofen, in contrast to etodolac, caused a reduction in PRC, suggesting that COX-1 is involved in basal renin release in humans
Harris et al., Acta Physiol Scand 2004 : In isolated perfused glomerular preparations, renin release induced by macula densa perfusion with a low chloride solution was inhibited by a COX-2 inhibitor but not a COX-1 inhibitor