McCulloch et al., Ann N Y Acad Sci 2000
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Differential activation of phospholipase D by VPAC and PAC1 receptors
McCulloch et al., Mol Pharmacol 2001
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Here we report that rat VPAC and PAC(1) receptors can also stimulate PLD ( albeit less potently than adenylate cyclase ) in transfected cells and also in cells where they are natively expressed
Ronaldson et al., Regul Pept 2002
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We have recently reported that the rat VPAC(1), VPAC(2) and PAC(1) receptors activate phospholipase D and that distinct pathways are utilised by two intracellular loop 3 splice variants of PAC(1), one of which is ARF dependent