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KSR1 — NRAS

Pathways - manually collected, often from reviews:

• NCI Pathway Database PDGFR-beta signaling pathway: KSR (KSR1) → RAS family/GTP complex (HRAS_KRAS_HRAS_KRAS_NRAS) (modification, activates)
  Ory et al., Curr Biol 2003, Tran et al., J Biol Chem 2005, McKay et al., Proc Natl Acad Sci U S A 2009, Ritt et al., Mol Cell Biol 2010, Muslin et al., Cell 1996
  Evidence: assay, physical interaction
• NCI Pathway Database ErbB1 downstream signaling: KSR (KSR1) → RAS family/GTP complex (HRAS_KRAS_HRAS_KRAS_NRAS) (modification, activates)
  Xing et al., J Biol Chem 2001*, Zhu et al., Mol Biol Cell 2005, Zang et al., J Biol Chem 2008*, Dhillon et al., Cell Signal 2009, App et al., Mol Cell Biol 1991*, Zheng et al., Biochemistry 1994*, Warne et al., Nature 1993*, Moodie et al., Science 1993*, Tzivion et al., Nature 1998*
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database PDGFR-beta signaling pathway: KSR (KSR1) → RAS family/GTP complex (HRAS_KRAS_HRAS_KRAS_NRAS) (modification, activates)
  Mason et al., EMBO J 1999, Ory et al., Curr Biol 2003, McKay et al., Proc Natl Acad Sci U S A 2009, Dhillon et al., Cell Signal 2009, Ritt et al., Mol Cell Biol 2010, Michaud et al., Mol Cell Biol 1995, Muslin et al., Cell 1996
  Evidence: assay, physical interaction
• NCI Pathway Database ErbB1 downstream signaling: KSR (KSR1) → RAS family/GTP complex (HRAS_KRAS_HRAS_KRAS_NRAS) (modification, activates)
  McKay et al., Proc Natl Acad Sci U S A 2009, Lange-Carter et al., Science 1994*
  Evidence: assay