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MOK — TXNIP

Text-mined interactions from Literome

Perrone et al., J Cell Physiol 2009 (Diabetes Mellitus, Experimental...) : Herein we investigate whether HG and RAGE induce inflammation in rat retinal endothelial cells ( EC ) under diabetic conditions in culture through TXNIP activation and whether epigenetic mechanisms play a role in inflammatory gene expression ... We show that RAGE activation by its ligand S100B or HG treatment of retinal EC induces the expression of TXNIP and inflammatory genes such as Cox2, VEGF-A, and ICAM1
Sbai et al., J Cell Sci 2010 : Moreover, we demonstrate for the first time that RAGE induces the expression of thioredoxin interacting protein (TXNIP) in SCs and the injured sciatic nerve in vivo