Gene interactions and pathways from curated databases and text-mining

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BACE1 — MOK

Text-mined interactions from Literome

Cho et al., FASEB J 2009 (Alzheimer Disease...) : RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer 's disease animal model ... NFAT1 was activated following RAGE induced BACE1 expression followed by Abeta generation ... Taken together, RAGE stimulates functional BACE1 expression through NFAT1 activation, resulting in more Abeta production and deposition in the brain
Guglielmotto et al., Neurobiol Aging 2012 (Alzheimer Disease...) : AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation