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BACE1 — MOK
Text-mined interactions from Literome
Cho et al., FASEB J 2009
(Alzheimer Disease...) :
RAGE regulates
BACE1 and Abeta generation via NFAT1 activation in Alzheimer 's disease animal model ... NFAT1 was activated following
RAGE induced
BACE1 expression followed by Abeta generation ... Taken together,
RAGE stimulates functional
BACE1 expression through NFAT1 activation, resulting in more Abeta production and deposition in the brain
Guglielmotto et al., Neurobiol Aging 2012
(Alzheimer Disease...) :
AGEs/RAGE complex
upregulates BACE1 via NF-?B pathway activation