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IRF6 — TYK2

Text-mined interactions from Literome

Xu et al., Mol Immunol 2008 : In addition, PTP1B inhibits LPS induced Tyk2 and STAT1 activation
Vogl et al., BMC genomics 2010 : Although Tyk2 is essential for the full LPS response, its function is mainly required for baseline expression but not LPS induced upregulation of IFN-inducible genes
Roy et al., J Biol Chem 2011 (Keratitis...) : Interferon-gamma induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter
Gong et al., Evidence-based complementary and alternative medicine : eCAM 2013 : LPS activated Tyk2 responsible for eotaxin-1 induction, while kaempferol dose-dependently inhibited LPS- or IL-8 inflamed Tyk2 activation