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IRF6 — SLC25A10

Text-mined interactions from Literome

Izutani et al., Biol Pharm Bull 2000 (Disseminated Intravascular Coagulation) : We compared urinary protein C inhibitor ( uPCI ) with low molecular weight heparin ( LMWH ) in terms of the effect on the pathophysiology of disseminated intravascular coagulation ( DIC ), such as hypercoagulation, induction of secondary fibrinolysis and organ failure, using lipopolysaccharide (LPS) induced DIC in rats
Asakura et al., Thromb Haemost 2001 (Disease Models, Animal...) : Beneficial effect of the active form of vitamin D3 against LPS induced DIC but not against tissue-factor induced DIC in rat models ... The results suggested that vitamin D3 was useful for the treatment of LPS induced DIC , and that the assessment of a drug 's efficacy should be done carefully given the markedly different results obtained according to the agents used to induce DIC
Asakura et al., Blood Coagul Fibrinolysis 2003 (Disease Models, Animal...) : In the present paper, we evaluate the characteristics of TF-induced and LPS induced DIC using two types of DIC models, with special reference to selected hemostatic parameters and pathological findings within the kidney ... Since the time course of the pathophysiology differed remarkably among the TF-induced and LPS induced DIC models in rats, we recommend that TF-induced and LPS induced DIC be approached as distinct models in order to determine the implications of their experimental and clinical use
Maruyama et al., Nihon rinsho. Japanese journal of clinical medicine 1992 (Disseminated Intravascular Coagulation...) : Soluble rTM also improved the consumption of fibrinogen and platelets in experimental DIC-rats induced by LPS
Asakura et al., Int J Hematol 2004 (Disseminated Intravascular Coagulation) : The present study was performed to clarify the role of DD in a rat model of lipopolysaccharide (LPS) induced DIC in which low-molecular-weight heparin ( LMWH ) and tranexamic acid ( TA ) were used ... LMWH demonstrated a protective effect against LPS induced DIC , resulting in increased survival at 12 hours, whereas TA had the opposite effect ... From these results, it appears that LMWH protects against LPS induced DIC , but TA exacerbates LPS induced DIC
Suga et al., Blood Coagul Fibrinolysis 2004 (Disseminated Intravascular Coagulation) : Our results suggest that vasoconstriction, as well as depressed fibrinolysis, contribute to severe organ dysfunction in LPS induced, but not thromboplastin induced, DIC, and that endothelin plays a role in the development of organ injury in LPS induced DIC in rats
Asakura et al., Intensive Care Med 2004 (Disseminated Intravascular Coagulation) : We examined the role of coagulation and fibrinolysis in lipopolysaccharide (LPS) induced disseminated intravascular coagulation ( DIC ) in rats, studying their contribution to fibrin deposition and organ failure in rats with LPS induced DIC by concurrent administration of low molecular weight heparin ( LMWH ) with or without tranexamic acid ( TA )
Pyo et al., Arzneimittelforschung 2004 (Disseminated Intravascular Coagulation) : The effects of 1- ( alpha-naphthylmethyl ) -6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline ( YS-49, CAS 132836-42-1 ) and 1- ( beta-naphthylmethyl ) -6,7-dihydroxy-1,2,3,4-tetra-hydroisoquinoline ( YS-51, CAS 213179-96-5 ) on the experimental DIC induced by lipopolysaccharide (LPS) in rats, were investigated
Asakura et al., Journal of thrombosis and haemostasis : JTH 2005 (Disseminated Intravascular Coagulation) : We then investigated the effect of L-NIL ( 6 mg kg ( -1 ), from - 0.5 to 4 h ) on LPS induced DIC ... Our results suggest that NO induced by iNOS contributes to hypotension ( depressed MAP ), the progression of hepatic and renal dysfunction, microthrombus deposition and elevated endothelin levels in the rat model of LPS induced DIC
Lin et al., Translational research : the journal of laboratory and clinical medicine 2007 (Disease Models, Animal...) : These findings suggest that the effects of FII ( a ) on LPS induced DIC were from fibrinogen degradation and enhanced protein C activity
Wang et al., Thromb Res 2009 (Disease Models, Animal...) : Novel recombinant fibrinogenase of Agkistrodon acutus venom protects against LPS induced DIC ... We observed that rFII increased survival rate in LPS induced DIC rabbits as well as heparin did
Lin et al., Int J Radiat Biol 2009 (Disseminated Intravascular Coagulation) : The aim of this study is to test whether static magnetic field (SMF) is effective in attenuating lipopolysaccharide (LPS) induced DIC
Ito et al., Thromb Res 1990 (Disseminated Intravascular Coagulation) : These observations suggest that drugs which inhibit platelet activation by a TxA2 dependent route are effective in improving DIC induced by LPS , and that drugs which inhibit multiple platelet activating routes improve DIC in more item parameters than drugs which inhibit only the TxA2 dependent activating route ... Consequently, it is concluded that activated platelets might play an important role in the occurrence and exacerbation of DIC induced by LPS , and that one of the roles of TxA2 in DIC is to activate platelets
Yuan et al., Sichuan Da Xue Xue Bao Yi Xue Ban 2010 (Disease Models, Animal...) : Urokinase could play a positive role to prevent the LPS induced DIC
Qi et al., Biochem Pharmacol 2012 (Disseminated Intravascular Coagulation...) : To better understand the mechanism of treatment on DIC, we here report a novel fibrinogenase from Agkistrodon acutus ( FIIa ) that effectively protected against LPS induced DIC in a rabbit model, and detected the tissue factors expression in HUVE cells after using FIIa
Yu et al., Thromb Res 2013 : In this study, we evaluated the protective effect of quercetin on LPS induced experimental DIC in rabbits, and tried to clarify its mechanism against DIC ... Quercetin may have a protective effect against LPS induced DIC in rabbits through anti-inflammation and anticoagulation
Dickneite et al., Thromb Res 1995 (Disseminated Intravascular Coagulation...) : In a rat model of lethal LPS induced DIC CRC 220 significantly prevented the mortality rate after a 4h-infusion of 0.75 mg/kg x h. Thrombin induced platelet aggregation in rat lungs could be prevented by the i.v. bolus injection of CRC 220