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ELF2 — IL8
Text-mined interactions from Literome
McElvaney et al., J Clin Invest 1992
(Cystic Fibrosis...) :
Human bronchial epithelial cells exposed to CF ELF recovered before rSLPI therapy expressed IL-8 mRNA transcripts, but
ELF recovered after rSLPI therapy
induced far less bronchial epithelial cell
IL-8 gene expression
Nakamura et al., J Clin Invest 1992
(Cystic Fibrosis) :
CF
ELF contained high levels of neutrophil elastase ( NE ) and various serine protease inhibitors
prevented CF ELF from inducing
IL-8 gene expression in BET-1A cells, suggesting that NE was the dominant inducer for IL-8 production in CF ELF