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IL6 — PLA2G1B

Text-mined interactions from Literome

Vadas et al., Infect Immun 1992 (Malaria) : Since both interleukin 1 and tumor necrosis factor induce expression of the proinflammatory enzyme phospholipase A2 (PLA2) , we examined serum PLA2 levels in 14 adults with malaria
Mühl et al., FEBS Lett 1992 : In contrast, interleukin-6 did not increase PLA2 mRNA levels of PLA2 activity
Assogba et al., Eur J Med Chem 2005 : It is also able to block the PLA2-II activities induced by LPS and IL-6 in HepG2 cell line and no cytotoxicity is observed when PMS1062 is tested up to a concentration of 100 microM in two different cell lines ( A549 and LLC-PK1 )
Chang et al., Neurosci Lett 2009 : These results suggested that PLA(2) activation was required for MeHg to induce glial IL-6 release
Bickford et al., J Cyst Fibros 2013 (Aspergillosis, Allergic Bronchopulmonary...) : Interestingly, PLA2G2D was induced by LPS, IL-2, IL-6 , IL-13, and Af only in CFTR-deficient human IB3.1 cells
Gilman et al., Agents Actions 1987 : Phospholipase A2 activation by interleukin 1 : release and metabolism of arachidonic acid by IL 1-stimulated rabbit chondrocytes
Godfrey et al., Prostaglandins 1988 (Osteoarthritis) : Recombinant interleukin-1 induced an approximate 3-fold increase in [ 3H ] -AA release, a 7-fold increase in PGE2 production and a 2-fold increase in PLA2 activity in human synovial fibroblasts ... These data show that tumor necrosis factor and interleukin-1 can both activate synovial cell PLA2 and induce generation of PGE2, but act in an additive rather than a synergistic fashion
Keuter et al., J Infect Dis 1995 (Typhoid Fever) : The 14-kDa group II extracellular phospholipase A2 (PLA2) is induced by interleukin-1 and tumor necrosis factor and may mediate some of the effects of these cytokines
Vervoordeldonk et al., Biochim Biophys Acta 1994 : Under conditions where 14 kDa group II PLA2 activity and protein levels were dramatically affected by interleukin-1 and dexamethasone, the level of annexin I in the cells remained constant
Yamashita et al., Biochem Biophys Res Commun 1994 (Adenocarcinoma...) : To investigate the role of group II phospholipase A2(PLA2) in cancer, we examined the expression and secretion of group II PLA2 in response to the stimulation of interleukin 6 ( IL-6 ) in human gastric cancer cells in vitro
Endo et al., Res Commun Mol Pathol Pharmacol 1995 (Sepsis) : The results suggest that TNF-alpha and IL-6 stimulate the production of type II PLA2 in the plasma of patients with sepsis