Liu et al., J Invest Dermatol 2002
:
Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1 , bacteria, and the state of differentiation
Niyonsaba et al., J Immunol 2005
(MAP Kinase Signaling System) :
We also revealed that hBD-2 , -3, and -4 and LL-37 increased IL-18 mRNA expression, and that IL-18 secretion was more enhanced in keratinocytes differentiated in vitro with high Ca2+ containing medium