Gene interactions and pathways from curated databases and text-mining

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E2F1 — ESCO2

Text-mined interactions from Literome

Wang et al., Cancer Res 2004 (Prostatic Neoplasms) : Coexpressed AR did not detectably change RB's regulation of E2F and cell cycle progression in culture
Schmitz et al., Leukemia 2005 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : Different cyclin dependent kinases (CDKs) sequentially phosphorylate and inactivate Rb, which is associated by a change in Rb's nuclear affinity and activation of E2F transcription