Gene interactions and pathways from curated databases and text-mining

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CDK2 — CRK

Text-mined interactions from Literome

Lee et al., J Cell Biochem 2006 : In addition, PD 98059 ( a MEK inhibitor ), SB 203580 ( a p38 MAPK inhibitor ), and SP 600125 ( a JNK inhibitor ) blocked the EGF induced stimulation of [ 3H ] -thymidine incorporation and CDK-2/4 expression
Taniguchi Ishikawa et al., Proc Natl Acad Sci U S A 2012 : Cell cycle quiescence is associated with down-regulation of cyclin D1, up-regulation of the cyclin dependent kinase inhibitors, p21 ( cip1. ) and p16(INK4a), and Forkhead transcriptional factor 1 ( Foxo1 ), and activation of p38 mitogen activated protein kinase ( MAPK ), indicating that H-Cx43-deficient HSCs are prone to senescence