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CDK2 — CRK
Text-mined interactions from Literome
Lee et al., J Cell Biochem 2006
:
In addition, PD 98059 ( a MEK inhibitor ), SB 203580 ( a
p38 MAPK inhibitor ), and SP 600125 ( a JNK inhibitor )
blocked the EGF induced stimulation of [ 3H ] -thymidine incorporation and
CDK-2/4 expression
Taniguchi Ishikawa et al., Proc Natl Acad Sci U S A 2012
:
Cell cycle quiescence is associated with down-regulation of cyclin D1, up-regulation of the
cyclin dependent kinase inhibitors, p21 ( cip1. ) and p16(INK4a), and Forkhead transcriptional factor 1 ( Foxo1 ), and
activation of
p38 mitogen activated protein kinase ( MAPK ), indicating that H-Cx43-deficient HSCs are prone to senescence