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CD40LG — MITF
Text-mined interactions from Literome
Matsumoto et al., J Biol Chem 2001
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Moreover, the overexpression of
MITF and Pip functionally
stimulated TRAP promoter activity in a synergistic manner
Meadows et al., J Biol Chem 2007
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MITF regulation of the
TRAP , cathepsin K, Clcn7, and Ostm1 genes, which are critical for osteoclast resorption, suggests that the role of MITF is more significant than previously perceived and that MITF may be a master regulator of osteoclast function and bone resorption
Choi et al., Cell Signal 2013
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These results strongly suggest that caffeine directly enhances osteoclast differentiation and maturation through p38 MAP kinase activation, thus
inducing Mitf expression and transcriptional activation of DC-STAMP, and finally CtsK and
TRAP