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AHR — TCF20

Text-mined interactions from Literome

Qin et al., Dev Biol 2004 : Additionally, we show that ahr-1 expression is regulated by the UNC-86 transcription factor
Boverhof et al., Mol Pharmacol 2006 : Many, if not all, of these effects involve changes in gene expression mediated via the activation of the aryl hydrocarbon receptor (AhR) , a ligand activated transcription factor
Karchner et al., Proc Natl Acad Sci U S A 2006 : The mechanism of HAH toxicity involves altered gene expression subsequent to activation of the aryl hydrocarbon receptor (AHR) , a basic helix-loop-helix-PAS transcription factor
Jensen et al., Mol Pharm 2006 (Adenocarcinoma...) : The aryl hydrocarbon receptor (AhR) is a ligand activated transcription factor which requires heterodimerization with the Ah receptor nuclear translocator (Arnt) for function
Sutter et al., Proc Natl Acad Sci U S A 2009 : Most of the effects of dioxin are attributed to its activation of the aryl hydrocarbon receptor (AHR) , a transcription factor that binds to the Ah receptor nuclear translocator (ARNT) to regulate the transcription of numerous genes, including CYP1A1 and CYP1B1
Mitchell et al., Toxicology 2010 (Hyperplasia) : Previous studies demonstrate that exogenous activation of the aryl hydrocarbon receptor (AhR) , a soluble ligand activated transcription factor in the basic helix-loop-helix family of proteins, suppresses compensatory liver regeneration elicited by surgical partial hepatectomy
Diani-Moore et al., J Biol Chem 2010 : All TCDD toxicities require activation of the aryl hydrocarbon receptor (AHR) , a ligand activated transcription factor
Sekimoto et al., Yakugaku Zasshi 2011 : We found that : 1 ) newly established reporter cell lines, HepG2-A10 and KanR2-XL8, can be used for determining of activation of the aryl hydrocarbon receptor (AhR) , a key transcription factor in the expression of CYP1As ; 2 ) monocyclic aromatic amine ( 2-methoxy-4-nitroaniline ) induced hepatic CYP1As in rats but not in other rodents in an AhR independent manner ; 3 ) androgen suppressed the constitutive expression or heterocyclic aromatic amine ( Trp-P-1 ) -dependent induction of these enzymes in pigs and mice ; and 4 ) nicardipine, a dihydropyridine calcium channel blocker, increased hepatic CYP1A expression in rats and augmented 3-methylcholanthrene mediated induction of CYP1As and DNA-adduct formation in HepG2 cells
Vrba et al., Phytother Res 2012 : The natural flavonoid quercetin is a low affinity ligand of the aryl hydrocarbon receptor (AhR) , a transcription factor regulating the expression of cytochrome P450 (CYP) 1A enzymes
Frauenstein et al., Cell Death Differ 2013 : We have discovered that the aryl hydrocarbon receptor (AHR) , a key regulator of drug metabolism and an UVB-sensitive transcription factor , serves an anti-apoptotic function in UVB irradiated human KC. Chemical and shRNA mediated inhibition of AHR signaling sensitized KC to UVB induced apoptosis by decreasing the expression of E2F1 and its target gene checkpoint kinase 1 (CHK1)