Gene interactions and pathways from curated databases and text-mining

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BTK — RAC1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Inabe et al., FEBS Lett 2002 (Agammaglobulinemia) : Here we show that the BCR mediated Rac1 activation is significantly inhibited by loss of Btk , while this Rac1 activation is not affected by loss of phospholipase C-gamma2 ( PLC-gamma2 )
Kuehn et al., J Cell Sci 2010 : Btk dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells