Gene interactions and pathways from curated databases and text-mining

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PIP — PTEN

Text-mined interactions from Literome

Solari et al., Oncogene 2005 : Furthermore, we provide genetic and biochemical evidence that dauer and lifespan control depends on PTEN mediated regulation of PIP3 levels
Vazquez et al., Cell cycle (Georgetown, Tex.) 2006 (Neoplasms) : PTEN activity to prevent elevated levels of PIP3 and tumorigenesis depends on its interaction with the lipid bilayer
Sha et al., Hear Res 2010 : PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse
Wan et al., J Biol Chem 2011 (Long QT Syndrome) : In guinea pig ventricular myocytes, even a modest reduction in PTEN activity is sufficient to increase cellular PIP ( 3 ) levels