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HSPG2 — PDGFB

Pathways - manually collected, often from reviews:

• Reactome Reaction: PDGFB → HSPG2 (indirect_complex) Knox et al., J Biol Chem 2002*
• Reactome Reaction: PDGFB → HSPG2 (reaction) Knox et al., J Biol Chem 2002*

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: HSPG2 — PDGFB (direct interaction, pull down) Göhring et al., Eur J Biochem 1998*
• IRef Hprd Interaction: PDGFB — HSPG2 (in vitro) Göhring et al., Eur J Biochem 1998*
• IRef Ophid Interaction: HSPG2 — PDGFB (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Kim et al., Biochem Pharmacol 2005 : Pre-incubation of rat aortic VSMCs with luteolin significantly inhibited the PDGF-BB induced extracellular signal regulated kinase 1/2 ( ERK1/2 ), Akt and phospholipase C (PLC)-gamma1 activation as well as c-fos gene expression
Kim et al., Arch Pharm Res 2006 : Pre-incubation of the VSMCs with L7G significantly inhibited the PDGF-BB induced extracellular signal regulated kinase 1/2 ( ERK1/2 ), Akt and the phospholipase C (PLC)-gamma1 activation