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PARP2 — XRCC5
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ariumi et al., Oncogene 1999
:
Thus,
DNA-PK suppresses
PARP activity, probably through direct binding and/or sequestration of DNA-ends which serve as an important stimulator for both enzymes
Veuger et al., Oncogene 2004
:
The inhibitory
effect of
DNA-PK on
PARP activity was confirmed in permeabilized cells
Ruscetti et al., J Biol Chem 1998
:
The protein kinase activity of
DNA-PK can be
stimulated by
PARP in the presence of NAD+ in a reaction that is blocked by the PARP inhibitor 1, 5-dihydroxyisoquinoline