Gene interactions and pathways from curated databases and text-mining

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NOX5 — PTX3

Text-mined interactions from Literome

Coimbra et al., J Trauma 2004 (Sepsis) : These results suggest that PTX-inhibition of oxidative burst occurs distal to PKC and may be either due to direct inhibition of NADPH oxidase or inhibition of MAPK phosphorylation, leading to decreased adhesion molecule expression and TNF-alpha synthesis
Ranjbar et al., Hum Exp Toxicol 2010 : In brain mitochondria, malathion enhanced LPO, NOx , CAT, GPx, and MnSOD and decreased GSH/GSSG as compared to controls, whereas PTX and AT restored malathion induced changes in GSH/GSSG, NOx, GPx, and CAT
Vaziri et al., Am J Physiol 1998 (Kidney Failure, Chronic) : Calcium channel blockade and PTX lowered blood pressure, increased urinary NOX , and enhanced vascular NOS activity, as well as eNOS and iNOS protein expressions in the tested tissues