Gene interactions and pathways from curated databases and text-mining

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MMP9 — TGFB3

Text-mined interactions from Literome

Gallery et al., Microvasc Res 1999 (Pre-Eclampsia...) : Neither tumor necrosis factor-alpha nor transforming growth factor-beta , both thought to have significant roles in the control of placentation, affected MMP secretion
Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Nuttall et al., Endocrinology 2000 : There was no effect of these growth factors on gelatinase or TIMP-1, -2, and -3, nor was there an effect of transforming growth factor-beta on any MMP or TIMP examined
Parkin et al., Eur J Ophthalmol 2000 (Keratoconus) : It is known that platelet derived growth factor ( PDGF ) and transforming growth factor-beta ( TGF-beta ) are involved in the regulation of MMP activity and tissue inhibitor of metalloproteinase ( TIMP ) production in non-ocular tissues
Han et al., J Biol Chem 2001 : In this report we demonstrate that tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta ( TGF-beta ) synergistically induce pro-MMP-9 in human skin as well as isolated dermal fibroblasts and epidermal keratinocytes
Blavier et al., Mol Biol Cell 2001 (Cleft Palate) : In concordance with these findings, MMP-13 expression was strongly induced by TGF-beta3 in palatal fibroblasts
Hosokawa et al., J Dent Res 2003 (Cicatrix...) : In tandem, TGF-beta 3 induced the expression and activity of MMP-9
Do et al., Mol Cancer Res 2008 (Neoplasm Metastasis...) : When cancer cells were cultured on plastic, TGF-beta1, TGF-beta2, and TGF-beta3 induced pro-matrix metalloproteinase ( MMP ) secretion, loss of cell-cell junctions, down-regulation of E-cadherin, up-regulation of N-cadherin, and acquisition of a fibroblastoid phenotype, consistent with an epithelial-to-mesenchymal transition ... When cancer cells were cultured on a three-dimensional collagen matrix, TGF-beta1, TGF-beta2, and TGF-beta3 stimulated both pro-MMP and active MMP secretion and invasion
Martinez-Alvernia et al., Ann Otol Rhinol Laryngol 2008 : Exogenous TGF-beta3 reestablishes production of at least MMP-9 , and probably MMP-2, in cricoid cartilages missing luminal perichondrium
Martinez-Alvernia et al., Otolaryngol Head Neck Surg 2010 : When both the LE and perichondrium are disrupted, matrix metalloproteinase ( MMP ) levels within adjacent chondrocytes are diminished but can be restored by exogenous TGF-beta3
Shimizu et al., Cancer Res 1996 (Carcinoma...) : Secretion of gelatinase B by LuM1 cells was augmented by tumor necrosis factor alpha, transforming growth factor beta1 ( TGF-beta1 ), interleukin 1beta, or epidermal growth factor, and specific neutralizing antibodies abolished the induced increases