Gene interactions and pathways from curated databases and text-mining

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MMP9 — SNAP25

Text-mined interactions from Literome

Burrow et al., J Surg Res 2007 (Diabetes Complications...) : SNAP and SNOG dose-dependently reduced MMP-8 and -9 mRNA expression in both normal and diabetic fibroblasts through day 7
Guo et al., Cell Biol Int 2011 (Carcinoma, Hepatocellular...) : SNAP ( S-nitroso-N-acetylpenicillamine ), a NO ( nitric oxide ) donor, and 8-Br-cGMP ( 8-bromo-cGMP ) inhibited thapsigargin induced Ca2+ entry and MMP secretion in the invasive potential of human SMMC-7721 cells
Lozito et al., J Cell Physiol 2012 : MPs lacked the MMP inhibitors TIMP-1 and TIMP-2 found in the Sup and, while Sup strongly inhibited MMP activities but MPs did not
Meschiari et al., Mol Cell Biochem 2013 : We studied the effects of DetaNONOate ( 10-400 µM ) or SNAP ( 50-400 µM ) on phorbol 12-myristate 13-acetate ( PMA ; 10 nM ) -induced increases in MMP-9 activity ( by gel zymography ) or concentrations ( by ELISA ) as well as on a tissue inhibitor of MMPs' (TIMP)-1 concentrations ( by ELISA ) in the conditioned medium of HUVECs incubated for 24 h with these drugs