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MMP9 — PDLIM7

Text-mined interactions from Literome

Takeshita et al., J Virol 1999 : The induction of MMP-9 expression by LMP-1 and both CTAR-1 and CTAR-2 mutants was blocked by the overexpression of IkappaB ... These data indicate that the activation of both the NF-kappaB and AP-1 pathways by LMP-1 , CTAR-1, and CTAR-2 is necessary for the activation of MMP-9 expression
Murono et al., Cancer Res 2000 (Neoplasm Invasiveness...) : Because we have shown that EBV latent membrane protein 1 (LMP1) enhances MMP-9 expression by activation of nuclear factor (NF)-kappaB and activator protein (AP)-1 ( T. Yoshizaki, et al., Proc. Natl. Acad. Sci. USA, 95 : 3621-3626, 1998 ), we therefore tested whether up-regulation of MMP-9 by LMP1 could be correlated with enhanced invasiveness of tumor cells in vitro ... Whether aspirin and sodium salicylate could reduce invasiveness and whether LMP1 could enhance MMP-9 expression in tumors grown in nude mice were also tested ... Treatment with aspirin or sodium salicylate inhibited invasiveness of the LMP1 expressing C33A cells ( P < 0.03 ) and suppressed both the LMP1 induced MMP-9 expression in zymographic analyses and LMP1 induced MMP-9 promoter activity in CAT reporter assays ( P < 0.01 )
Wang et al., Zhonghua Zhong Liu Za Zhi 2002 (Nasopharyngeal Neoplasms) : [ Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus LMP1 via NF-kappa B or AP-1 signaling pathway in nasopharyngeal carcinoma cells ] ... To determine whether LMP1 or its mutants contribute to MMP9 production via NF-kappa B or AP-1 transcription factor, MMP9-chloramphenicol acetyl transferase (CAT), NF-kappa B mut 9-CAT, AP-1 mut MMP9-CAT were transfected into human nasopharyngeal carcinoma cells stably expressing LMP1 ( HNE2-LMP1 ) or its mutants, [ HNE2-LMP1 ( 1-185 ), HNE2-LMP1 ( 1-231 ), HNE2-LMP1 delta 187-351 ] by electroporation technic
Gou et al., Chin J Cancer 2003 (Nasopharyngeal Neoplasms...) : It has been proved that Epstein- Barr virus ( EBV ) latent membrane protein 1 ( EBV-LMP1 ) can induce the expression of matrix metalloproteinase-9 (MMP-9) ... The transfection of LMP1 can increase the expression of MMP-9 in CNE1 cells
Boya et al., J Exp Med 2003 : LMP triggers mitochondrial membrane permeabilization ( MMP ) , as detected by the release of cytochrome c ... Bax-/- Bak-/- double knockout cells fail to undergo MMP and cell death in response to CPX- or NFX induced LMP
Liu et al., Oncogene 2003 (Nasopharyngeal Neoplasms...) : First, restoration of RECK expression by PD98059 reduced LMP1 induced release of active MMP-9
Lee et al., Biomed Pharmacother 2007 (Carcinoma...) : To investigate the role of LMP1 in MMP expression in NPC, we cloned the LMP1 gene from NPC samples and transiently expressed it in MRC5 cells ( human lung fibroblasts )