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IL4 — MMP9

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Chizzolini et al., J Immunol 2000 : Although inhibitory on freshly isolated peripheral blood monocytes, soluble IL-4 enhanced T cell induced MMP-1 and inhibited MMP-9 production both at protein and mRNA levels in monocytes cultured for 7 days in the presence of GM-CSF
Beppu et al., Biochim Biophys Acta 2002 (Carcinoma, Squamous Cell...) : In the process of searching for agents to inhibit MMP-9 in cancer, immunosuppressive factors, dexamethasone ( DEX ) and interleukin-4 (IL-4) were found to inhibit protein production as well as gene expression of MMP-9 in tumor necrosis factor alpha (TNFalpha) stimulated SCC cells
Abraham et al., Int Immunol 2002 : All pro-inflammatory cytokines enhanced MT1-MMP expression and IL-4 suppressed TNF-alpha induced MMP-9 expression
Lee et al., J Allergy Clin Immunol 2003 (Asthma...) : These results suggest that MMP inhibitors regulate inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression and possibly also by suppressing IL-1beta, IL-4 , and TNF-alpha expression
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Corcoran et al., J Biol Chem 1992 : Additionally, we also assessed the effect of IL-4 on the production of 92-kDa type IV collagenase/gelatinase and tissue inhibitor of metalloproteinase-1 ( TIMP-1 ) by monocytes ... IL-4 also suppressed ConA stimulated 92-kDa type IV collagenase/gelatinase protein and zymogram enzyme activity that could be reversed by exogenous PGE2 or Bt2cAMP
Yang et al., Arthritis Rheum 2005 (Arthritis, Experimental...) : These data demonstrate the requirement of PAR-1 for the expression of AIA, the development of an antigen-specific Ig response, thrombin induced macrophage cytokine and MMP expression, and the inhibitory effect of PAR-1 on serum IL-4
Giannelli et al., J Interferon Cytokine Res 2006 : In this study, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha), commonly elevated in chronic C hepatitis, stimulate the production of matrix metalloprotease-9 (MMP-9) by human hepatocytes at a transcriptional and translational level, but the addition of recombinant interferon-alpha2b ( rIFN-alpha2b ) hampers this effect
Chi et al., Exp Cell Res 2010 (Lung Neoplasms) : These data suggest that IL-4 induced down-regulation of MMP-9 activity may contribute to up-regulation of 15-PGDH in A549 cells
Linde et al., PloS one 2012 (Carcinoma, Squamous Cell...) : IL-4 stimulation of macrophage containing cultures resulted in enhanced tumor cell invasion evidenced by degradation of the basement membrane, enhanced collagenolytic activity and increased MMP-2 and MMP-9
Alexander et al., Curr Eye Res 1998 : A phorbol mitogen ( TPA ), and TNF alpha and beta, interleukin-1 alpha and PDGF BB stimulate gelatinase B , stromelysin, interstitial collagenase and TIMP-1 expression, while having negligible effects on gelatinase A expression ; TIMP-2 levels are reduced by TNF but not affected by the other treatments