Gene interactions and pathways from curated databases and text-mining

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MMP2 — TYR

Text-mined interactions from Literome

Higashi et al., J Biol Chem 2003 : Studies of deletion of the NH ( 2 ) - and COOH-terminal residues and alanine replacement of internal residues of the decapeptide further revealed that Tyr ( 588 ), Asp ( 591 ), and Leu ( 593 ) of APP mainly stabilize the interaction between gelatinase A and the inhibitor
Menon et al., Am J Physiol Cell Physiol 2006 : Inhibition of MMP-2 using SB3CT, a selective gelatinase inhibitor, significantly increased FAK phosphorylation ( Tyr-397 and Tyr-576 )
Manosroi et al., J Nanosci Nanotechnol 2012 : The crude extracts were tested for antioxidative activities, tyrosinase inhibition and in vitro cytotoxicity as well as the MMP-2 inhibition activity on human skin fibroblasts for anti aging evaluation