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DERL1 — MMP2

Text-mined interactions from Literome

Liao et al., Biochemistry 2010 (Alzheimer Disease...) : Membrane type 1 (MT1) MMP is the physiological activator for the zymogen pro-MMP2
Dong et al., Am J Pathol 2013 (Carcinoma, Non-Small-Cell Lung...) : Derlin-1 overexpression up-regulated MMP-2/9 expression and ERK phosphorylation, which could be reversed by MAP kinase/ERK kinase inhibitor, PD98059 ... The effect of Derlin-1 on MMP-2/9 up-regulation was abolished in ERK1/2 siRNA treated cells