Garcia et al., Neuroscience 2004
(MAP Kinase Signaling System) :
In the present study, we used primary striatal neurons in culture to analyze c-Jun activation by Exp-Htt Taylor et al., J Neurosci 2013
(Huntington Disease) :
Overexpression of MKP-1 prevented the polyglutamine expanded huntingtin induced activation of c-Jun N-terminal kinases (JNKs) and p38 MAPKs, whereas extracellular signal regulated kinase ( ERK ) 1/2 activation was not altered by either polyglutamine expanded Htt or MKP-1