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AGTR2 — IRS2

Text-mined interactions from Literome

Cui et al., Mol Endocrinol 2002 : AT2 receptor stimulation increased the association of a protein tyrosine phosphatase, SHP-1, with IRS-2
Diamond-Stanic et al., Biochem Biophys Res Commun 2011 (Insulin Resistance) : In the presence of insulin, H2O2 decreased total protein expression of IRS-1 at 6 h and IRS-2 at 4 and 6 h. Phosphorylation of p38 MAPK Thr180/Tyr182 was transiently increased by H2O2 in the presence and absence of insulin at 2 and 4 h, but not at 6 h. Selective inhibition of p38 MAPK with A304000 partially rescued the H2O2 induced reduction in insulin stimulated glucose transport activity