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IRF6 — OCLN

Text-mined interactions from Literome

Park et al., J Pediatr Gastroenterol Nutr 2010 (Acute Disease...) : Dietary GGs reduced the degradation of occludin tight junction protein in response to LPS
Kolodziej et al., PloS one 2011 : Immunohistochemistry of mouse intestine revealed that TNFAIP3 expression inhibits LPS induced loss of the tight junction protein occludin from the apical border of the intestinal epithelium
Hou et al., Amino Acids 2012 (Weight Gain) : Moreover, NAC prevented the LPS induced decrease in claudin-1 and occludin expression in the jejunal and ileal mucosae
Zhou et al., Surgery 2013 : Here, GEF-H1 knockdown or ROCK inactivation both not only significantly inhibited LPS induced actin stress fiber formation, phosphorylation of myosin light chain, and myosin associated phosphatase type 1, but also suppressed LPS induced loss of occludin , claudin-1, and vascular endothelial (VE)-cadherin in ECs, which suggested that LPS induced stress fiber formation and cell-cell junctions disruption were closely associated with GEF-H1/RhoA/ROCK signaling activation