◀ Back to IRF6

IRF6 — NUP43

Text-mined interactions from Literome

Paul et al., Cell Signal 1999 : In RAW 264.7 macrophages lipopolysaccharide (LPS) stimulated the activation of p42 and p44 MAP kinases and their upstream activator mitogen activated protein ( MAP ) kinase kinase ( MAPKK ), and induced the 69-kDa isoform of cyclo-oxygenase-2 (COX-2) and the 130-kDa isoform of nitric oxide synthase (iNOS)
Chan et al., Am J Respir Cell Mol Biol 2001 (MAP Kinase Signaling System) : By contrast, in the presence of 10 % serum, NAC had no effect on LPS activation of p42 and p44 ERK and in fact enhanced LPS induction of p38mapk and JNK phosphorylation
van den Blink et al., Mol Med 2001 (Endotoxemia) : We observed that LPS induced a strong but transient phosphorylation and activation of p38 MAPK and p42/p44 MAPK, maximal activity being reached after 1 hr of LPS infusion
Lo et al., Carcinogenesis 2002 : Carnosol also inhibited LPS induced p38 and p44/42 mitogen activated protein kinase ( MAPK ) activation at a higher concentration ( 20 microM )
Carter et al., Shock 2002 (Disease Models, Animal...) : However, activation of both p44/42 and SAPK/JNK in response to LPS , was significantly lower in the SLH rats when compared to shams
Fiebich et al., J Neuroimmunol 2002 : Inhibition of LPS induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells
Heagy et al., Shock 2003 (MAP Kinase Signaling System) : LPS induced endotoxin-tolerance with a significant inhibition of LPS stimulated TNF secretion and less p44/p42 ERK kinase activation ... LPS stimulated p44/p42 ERK kinase activation and TNF release were diminished whether or not anti-CD14 antibody was present during LPS pretreatment ... LPS stimulated TNF secretion and p44/p42 ERK kinase activation require the presence of serum and are inhibited by anti-CD14 antibody
Chen et al., J Cell Physiol 2003 : Pretreatment of cells with either GSE or NAC increased the early LPS stimulated activation of p42/44 but had little effect on the sustained phase
Cheng et al., Toxicol Lett 2004 (Glioma) : Both Pb and LPS increased the phosphorylation of p42/44 mitogen activated protein kinase ( MAPK ), which depended on the activation of MAPK kinase ( MEK ) and protein kinase C ( PKC )
Gutiérrez-Venegas et al., Life Sci 2006 : Pretreatment of human gingival fibroblasts with antibodies anti-CD14 or anti-TLR-4 but not anti-TLR-2 inhibited the LPS induced tyrosine phosphorylation of p44 and p42 ... Additionally, LPS induced p44 and p42 phosphorylation was inhibited by polymyxin treatment ... These findings demonstrate that LPS from A. actinomycetemcomintans increases rapidly p44 and p42 phosphorylation ( ERK 1 and ERK 2, respectively ) in human gingival fibroblasts
Pan et al., Biochem Pharmacol 2006 (Cocarcinogenesis...) : We found that acacetin also inhibited LPS induced activation of PI3K/Akt and p44/42 , but not p38 MAPK
Liu et al., Appl Microbiol Biotechnol 2013 (Inflammation) : The blockade of LPS induced p42/44 and p38 MAPK signal pathway might contribute to the anti-inflammation effects of the DEFB126 core peptide
Arditi et al., J Immunol 1995 : LPS induced protein tyrosine phosphorylation in HBMEC and BBMEC was soluble CD14 dependent, since pretreatment of these cells with anti-hCD14 mAb inhibited the LPS induced tyrosine phosphorylation of p44, p42 , and p41
Zheng et al., Biochem Pharmacol 1994 : However, neither simultaneous treatment with THC nor pre- and simultaneous treatment had any effect on LPS induced tyrosine phosphorylation of p41 and p42 in macrophages