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CCR5 — IRF6

Text-mined interactions from Literome

Franchin et al., J Immunol 2000 (Calcium Signaling) : This LPS mediated down-regulation of CCR5 expression was independent of de novo protein synthesis and differed from the rapid turnover of these chemokine receptors observed in response to two natural ligands, macrophage-inflammatory protein-1alpha and -1beta
Juffermans et al., J Infect Dis 2000 : Thalidomide produced a dose dependent inhibition of lipopolysaccharide (LPS) induced up-regulation of CXCR4 and CCR5 in vitro
Juffermans et al., J Infect Dis 2002 (Endotoxemia...) : In whole blood in vitro, not only LPS but also lipoarabinomannan ( a cell wall component of Mycobacterium tuberculosis ) and lipoteichoic acid ( a cell wall component of Staphylococcus aureus ) down-regulated the expression of CXCR4 and CCR5 on monocytes ( all P < .05 ) ... To test the hypothesis that an LPS effect on CXC chemokine receptor 4 (CXCR4) and CC chemokine receptor 5 (CCR5) , known coreceptors for HIV, contributes to this effect, 8 healthy men were intravenously injected with Escherichia coli LPS ( 4 ng/kg ), and monocyte CXCR4 and CCR5 expression was monitored by fluorescence activated cell sorter analysis
Bosco et al., Cell Immunol 2004 : CCR5 upregulation by IL-10, LPS , and IL-4 was also antagonized by hypoxia
Amat et al., Br J Pharmacol 2006 (Arthritis) : Surprisingly, CCR1 knockout mice produced more TNFalpha than controls in response to LPS , and J-113863 decreased TNFalpha also in CCR1 null mice, indicating that its effect was unrelated to CCR1
Jiang et al., J Immunol 2007 : NGF could markedly promote LPS induced expression of HLA-DR, CD40, CD80, CD83, CD86, CCR7 , secretion of IL-12p40 and proinflammatory cytokines IL-1, IL-6, TNF-alpha, and the T cell stimulating capacity of MoDCs, indicating that NGF can promote LPS induced DC maturation
van de Laar et al., J Immunol 2010 : Although dispensable for costimulatory molecule expression, the PI3K-PKB-mTOR signaling module was required for other important processes associated with DC function, including Ag uptake, LPS induced cytokine secretion, CCR7 expression, and T cell stimulation
Sica et al., J Exp Med 1997 : The present study was designed to investigate the effect of bacterial lipopolysaccharide (LPS) on C-C chemokine receptors ( CCR ) expressed in human mononuclear phagocytes
Minami et al., Toxicology 1998 : We investigated the penetration of cisplatin into the mouse cerebral cortex-rich region ( CCR ) induced by lipopolysaccharide (LPS) ... At doses of 500 mg/kg aminoguanidine, however, no effect was seen on the platinum level of the CCR induced by LPS