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IL17D — TLR3

Text-mined interactions from Literome

Molle et al., J Immunol 2007 : IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3
Molle et al., J Immunol 2010 : Critical role of the IFN stimulated gene factor 3 complex in TLR mediated IL-27p28 gene expression revealing a two-step activation process ... Thus, in response to TLR4 or TLR3 ligation, the initial induction of the IL-27p28 gene depends on the recruitment of IRF1 and IRF3, whereas transcriptional amplification requires recruitment of the IFN stimulated gene factor 3 complex
Bosmann et al., J Immunol 2012 : In contrast, the PI3K/Akt pathway was not involved in TLR3 mediated release of IL-27 ( p28 )