Gene interactions and pathways from curated databases and text-mining

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IL13 — TCF21

Text-mined interactions from Literome

Madden et al., J Immunol 2002 : Binding of IL-4 by either the type 1 or 2 IL-4R, or of IL-13 by the type 2 IL-4R, initiates Jak dependent tyrosine phosphorylation of the IL-4Ralpha-chain and the transcription factor , STAT6
McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors
Palmer-Crocker et al., J Clin Invest 1996 : Furthermore, both IL-4 and IL-13 induce binding of the Stat6 transcription factor to a consensus sequence oligonucleotide
Manna et al., J Immunol 1998 : TNF induced activation of another nuclear transcription factor , AP-1, was suppressed by IL-13
Lentsch et al., J Immunol 1999 (Acute Disease...) : In the presence of anti-IL-13 , activation of the transcription factor , NF-kappaB, was significantly increased in lung