Gene interactions and pathways from curated databases and text-mining

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IL13 — MYLK

Text-mined interactions from Literome

Weber et al., J Biol Chem 2010 (Inflammatory Bowel Diseases) : Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity ... In vivo, MLCK activation increases paracellular flux of uncharged macromolecules and also triggers IL-13 expression, claudin-2 synthesis, and increased paracellular cation flux
Potì et al., Arterioscler Thromb Vasc Biol 2013 (Aortic Diseases...) : In vitro studies demonstrated that KRP-203 reduced tumor necrosis factor-a, interleukin-6 , and interferon-? induced protein-10 production ; I?B and signal transducer and activator of transcription-1 phosphorylation ; and nuclear factor ?B and signal transducer and activator of transcription-1 activation in poly ( I:C ) -, lipopolysaccharide-, or interferon-? stimulated bone marrow macrophages, respectively