Gene interactions and pathways from curated databases and text-mining

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CSF2 — EDN1

Text-mined interactions from Literome

Xu et al., Zhonghua Jie He He Hu Xi Za Zhi 1997 : [ The effect of GM-CSF on endothelin-1 and endothelin converting enzyme gene expression in human airway smooth muscle cells with or without theophylline incubation ] ... To explore the role of airway smooth muscle cells ( ASMC ) stimulated by inflammatory factors in the development of asthma and bronchial hyperresponsiveness ( BHR ) and the possible mechanism of low dose theophylline in the treatment of airway inflammation, the effects of GM-CSF on endothelin-1 and endothelin converting enzyme (ECE) gene expression in human ASMC and theophylline on their expressions were investigated
Namiki et al., Eur J Pharmacol 1992 : We examined the effect of human recombinant granulocyte-colony stimulating factor ( G-CSF ) on the release of immunoreactive endothelin-1 (ET-1) from cultured bovine vascular endothelial cells
Hosoki et al., Int Arch Allergy Immunol 2010 : GM-CSF significantly enhanced EDN release by CD but not by BB
Fujisawa et al., J Immunol 1990 : GM-CSF and rIL-3 also enhanced Ig-induced EDN release but less potently than rIL-5 ... GM-CSF and rIL-5 by themselves induced a small but significant release of EDN from eosinophils in the absence of Ig-coated beads ; rIL-3 did not
Mullol et al., Neuropeptides 1996 : Endothelin-1 induces GM-CSF , IL-6 and IL-8 but not G-CSF release from a human bronchial epithelial cell line ( BEAS-2B )
Sun et al., Peptides 1997 (Asthma) : We report here that asthmatic bronchial epithelial cells exposed to allergens in vitro induce the differentiation of airway fibroblasts into myofibroblasts, and that they do so through a granulocyte/macrophage colony stimulating factor mediated upregulation of endothelin-1 production
Nagata et al., Am J Respir Cell Mol Biol 1998 (Asthma...) : In the presence of GM-CSF , ICAM-1 and VCAM-1 caused significant release of EOS derived neurotoxin ( EDN )