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APOB — IL4
Text-mined interactions from Literome
Sasaki et al., Biol Pharm Bull 1999
:
The
effects of
interleukin (IL)-4 and IL-10 on macrophage growth stimulating activities of oxidized
low density lipoprotein (LDL) , acetylated LDL and macrophage colony stimulating factor : the activity of oxidized LDL is refractory to the inhibitory cytokines ... To learn further the physiological regulation of macrophage growth, we comparatively examined the
effect of
interleukin (IL)-4 and IL-10 which have been reported to be suppressive to various macrophage functions on macrophage growth stimulating activities of the acetyl-LDL, oxidized
LDL and macrophage colony stimulating factor ( M-CSF ) ... The growth inducing activity of
acetyl-LDL was significantly
inhibited by both
IL-4 and IL-10 ... On the other hand, the activity of oxidized
LDL was not
attenuated by
IL-4 or IL-10
Tapiero et al., Biomed Pharmacother 2004
(Cardiovascular Diseases...) :
In addition,
Ox-LDL enhances the production and release of tumor necrosis factor ( TNF-alpha ),
interleukin (IL)-6, arachidonic acid metabolites and nitric oxide ( NO ) that are responsible for various human pathologies including cancer