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AGTR2 — IRF1

Text-mined interactions from Literome

Goto et al., Hypertens Res 2002 (Genetic Predisposition to Disease...) : The expression of interferon regulatory factor (IRF)-1 paralleled the growth dependent induction of AT2 receptor in WKY mesangial cells, and transfection of IRF-1 antisense oligonucleotide significantly suppressed AT2 receptor expression, indicating IRF-1 dependent regulation of AT2 receptor expression in mesangial cells
Horiuchi et al., J Biol Chem 1995 : The growth dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2 ... Furthermore, by antisense treatment, we demonstrated that IRF-2 attenuated the AT2 receptor expression in both growing and confluent R3T3 cells, whereas IRF-1 enhanced AT2 receptor expression in the confluent cells only ... We conclude that, in confluent cells, the enhanced expression of IRF-1 antagonizes the IRF-2 effect and increases the AT2 receptor expression