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HSPD1 — MAPK6
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Sasu et al., Circ Res 2001
(Chlamydophila Infections) :
Together these results indicate that C pneumoniae and chlamydial
hsp60 are potent inducers of human VSMC proliferation and that these effects are
mediated , at least in part, by rapid TLR4 mediated activation of p44/p42
MAPK
Kim et al., Bone 2009
(Bone Resorption) :
Furthermore, Western blotting showed that HSP60 up-regulated TLR-2 and TLR-4 expression, and pretreatment with blocking antibodies for TLR-2 and TLR-4 almost completely eliminated the
effects of
HSP60 on apoptosis, caspase-3 and -9 activation, and activation of NFkappaB and p38
MAPK