Gene interactions and pathways from curated databases and text-mining

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HDC — IL3

Text-mined interactions from Literome

Schneider et al., Exp Hematol 1999 : IL-3 induced coexpression of histidine decarboxylase , IL-4 and IL-6 mRNA by murine basophil precursors
Yamaguchi et al., Toxicology 2000 (Inflammation) : Induction of histidine decarboxylase , the histamine forming enzyme, in mice by interleukin-12
Nakano et al., Nihon Yakurigaku Zasshi 2001 : Among the cytokines tested, GM-CSF or IL-3 specifically augmented the LPS dependent HDC induction by M phi
Wu et al., Int Immunopharmacol 2004 : Histamine production via mast cell independent induction of histidine decarboxylase in response to lipopolysaccharide and interleukin-1
Minkowski et al., Exp Hematol 1990 : It results from an increase in histamine synthesis because of 1 ) the low level of histamine cell content before any incubation, 2 ) the parallel increase in both extra- and intracellular histamine levels in response to rhIL-3, and 3 ) the early IL-3 induced increase in L-histidine decarboxylase ( HDC ; EC 4.1.1.22 ) activity
Schneider et al., J Immunol 1987 : Interleukin 3 and granulocyte-macrophage colony stimulating factor induce de novo synthesis of histidine decarboxylase in hemopoietic progenitor cells ... In response to GM-CSF, HDC activation is more rapid, with a significant enhancement after 4 hr of incubation, as compared with IL-3 induced HDC activation ... These results suggest that IL-3 and GM-CSF induce HDC activation in two distinct ways, possibly reflecting the involvement of distinct target cells ... Finally, the observation that cholera toxin, prostaglandin E2, and N6,2'-O-dibutyryl adenosine 3',5'-cyclic monophosphate mimic the effects of IL-3 and GM-CSF on bone marrow cell HDC suggests an involvement of cyclic adenosine monophosphate in factor induced histamine producing cell stimulating activity
Endo et al., Br J Pharmacol 1995 : Effects of macrophage depletion on the induction of histidine decarboxylase by lipopolysaccharide, interleukin 1 and tumour necrosis factor
Salachas et al., Blood 1994 : ( 2 ) Neither IL-3 nor IgE induced histamine production in the presence of the specific inhibitor of histidine decarboxylase (HDC) , the histamine forming enzyme ... ( 3 ) Both the enzymatic activity and the mRNA expression of HDC were enhanced in response to IL-3 or IgE
Endo et al., Calcif Tissue Int 1993 (Bone Resorption) : As granulocyte and granulocyte-macrophage colony stimulating factors and interleukin-3 induce HDC in hematopoietic organs, and histamine has a hematopoietic activity, the HDC induction by aminobisphosphonates may be relevant to the proliferation of progenitor cells of macrophages, granulocytes, and osteoclasts
Takamatsu et al., J Immunol 1996 : GM-CSF and IL-3 also caused a marked accumulation of both histidine decarboxylase and IL-6 mRNAs in the cells