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EGF — IL6
Text-mined interactions from Literome
Tokunou et al., Arterioscler Thromb Vasc Biol 2001
:
Pharmacological inhibition of extracellular signal regulated protein kinase ( ERK ), p38 mitogen activated protein kinase ( MAPK ), or
epidermal growth factor receptor (EGF-R) suppressed the thrombin induced
IL-6 expression
Deaciuc et al., Alcohol Clin Exp Res 2002
(Liver Diseases, Alcoholic) :
EGF did not
affect liver mRNA expression of TNF-alpha, IL-1beta,
IL-6 , and IL-10, which suggested that these cytokines were not involved in EGF protective effect
Halpern et al., J Pediatr Gastroenterol Nutr 2003
(Disease Models, Animal...) :
We have shown in previous studies that proinflammatory interleukin-18 and
interleukin-12 are up-regulated in the ileum of rats with experimental NEC and that
epidermal growth factor (EGF) reduces the development of disease
Le et al., J Exp Med 1991
:
Regulation of cytokine production in the human thymus :
epidermal growth factor and transforming growth factor alpha
regulate mRNA levels of interleukin 1 alpha (IL-1 alpha), IL-1 beta, and
IL-6 in human thymic epithelial cells at a post-transcriptional level
Yang et al., Exp Eye Res 2010
:
Neither
EGF nor WIN
induced any increases in
IL-6 and IL-8 release
Alberti et al., Oncogene 2012
(Neoplasms, Glandular and Epithelial...) :
A significant reduction of
EGF stimulated
IL-6/PAI-1 secretion was also obtained with the NFkB inhibitor dehydroxymethylepoxyquinomicin
Jones et al., Acta Endocrinol (Copenh) 1993
(Adenoma...) :
Interleukin-1 (IL-1) stimulated
IL-6 release after a 24-h incubation period in five of the seven IL-6 secreting adenoma cultures and in all seven after 72 h. Tumour necrosis factor, interferon-gamma and
epidermal growth factor did not significantly
affect IL-6 secretion
Wu et al., J Biol Chem 1996
:
In contrast, NGF and
EGF , in the
presence or absence of
IL-6 , cause mobility shifts of Stat3 that are consistent with serine phosphorylations
Schluns et al., J Immunol 1997
:
TGF-beta differentially modulates
epidermal growth factor mediated
increases in leukemia-inhibitory factor,
IL-6 , IL-1 alpha, and IL-1 beta in human thymic epithelial cells ... TGF-beta plus
EGF did not
affect transcription of LIF and
IL-6 genes ; this suggests that the increases in the steady state levels of cytokine mRNA were mediated post-transcriptionally, most likely at the level of mRNA stability
Murthy et al., J Lipid Res 1997
:
The results suggest that, in CaCo-2 cells,
IL-6 causes the release of
EGF or an EGF-like molecule