Gene interactions and pathways from curated databases and text-mining

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PTGS2 — TGFB3

Text-mined interactions from Literome

Fosslien et al., Ann Clin Lab Sci 2000 (Carcinoma, Squamous Cell...) : COX-2 is inducible by oncogenes ras and scr, interleukin-1, hypoxia, benzo [ a ] pyrene, ultraviolet light, epidermal growth factor, transforming growth factor beta , and tumor necrosis factor alpha
Sheng et al., J Biol Chem 2000 : Here we investigated the role of transforming growth factor-beta ( TGF-beta ) in the Ras mediated induction of COX-2 in intestinal epithelial cells ( RIE-1 )
Bradbury et al., Am J Physiol Lung Cell Mol Physiol 2002 (Anoxia...) : Bradykinin, transforming growth factor-beta1 ( TGF-beta1 ), and interleukin-1beta (IL-1beta) increased inducible COX-2 expression and prostaglandin E ( 2 ) ( PGE ( 2 ) ) release
Hiraga et al., Cancer Res 2006 (Bone Neoplasms...) : Stimulation of cyclooxygenase-2 expression by bone derived transforming growth factor-beta enhances bone metastases in breast cancer
Harding et al., Kidney Int 2006 : This study examines the hypothesis that transforming growth factor beta ( TGFbeta ) regulates cyclooxygenase-2 (COX-2) and induces prostaglandin E synthase ( mPGES-1 ) in rat mesangial cells
Guo et al., Dig Dis Sci 2008 : Synergistic regulation of COX-2 expression by bombesin and transforming growth factor-beta
Matsumura et al., J Biol Chem 2009 : Regulation of transforming growth factor-beta dependent cyclooxygenase-2 expression in fibroblasts
Roy et al., J Cell Biochem 1996 : Prostaglandin E2, transforming growth factor-beta , and interleukin-1 beta variably regulate the expression of cyclooxygenase 1, cyclooxygenase 2 , and lysyl oxidase in IMR90, human embryo lung fibroblasts
Sheng et al., Cell Growth Differ 1997 : Cyclooxygenase-2 induction and transforming growth factor beta growth inhibition in rat intestinal epithelial cells
Martín-Sanz et al., Br J Pharmacol 1998 : Also, transforming growth factor-beta inhibited the LPS- and pro-inflammatory cytokines dependent expression of COX-2