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PPP2R2B — SET

Text-mined interactions from Literome

Chohan et al., FEBS Lett 2006 : Memantine, an un-competitive inhibitor of N-methyl-D-aspartate receptors, inhibits this abnormal phosphorylation of tau and cell death and prevents the I2PP2A induced inhibition of PP2A activity in vitro ... These findings demonstrate novel mechanisms by which I2PP2A regulates the intracellular activity of PP2A and phosphorylation of tau, and by which Memantine modulates PP2A signaling and inhibits neurofibrillary degeneration
Bareford et al., Cancer Biol Ther 2012 (Breast Neoplasms...) : PP2A can be directly activated by ceramide and SET/I2PP2A can be inhibited by ceramide