Huang et al., Cancer Lett 2009
(Carcinoma...) :
Also, we found blockage mTORC1 inhibited Cyclin D1 expression in CNE-2 cells and enhanced cell apoptosis
Coiffier et al., Leukemia & lymphoma 2009
(Hematologic Neoplasms...) :
Mantle cell lymphoma ( MCL ) was the first hematologic malignancy in which mTOR inhibition was explored as a treatment strategy, owing to its characteristic overexpression of cyclin D1, a G1 cyclin regulated by mTOR signaling