Gene interactions and pathways from curated databases and text-mining

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NFKB1 — PLK1

Text-mined interactions from Literome

Cude et al., J Cell Biol 2007 : Furthermore, selective inhibition of NFkappaB at G2-M phases substantially delayed mitotic entry and inhibited transcription of G2-M-specific genes, including cyclin B1, cyclin B2, Plk-1 , and cdc25B
Zhang et al., Mol Biol Cell 2010 : The scaffold protein TANK/I-TRAF inhibits NF-kappaB activation by recruiting polo-like kinase 1 ... PLK1 inhibits NF-kappaB transcriptional activation induced by TNF-alpha, IL-1beta, or several activators, but not by nuclear transcription factor p65 ... PLK1 expression reduces the DNA binding activity of NF-kappaB induced by TNF-alpha