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EGR3 — JUN
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Levkovitz et al., J Neurosci 2001
:
Furthermore, the
Egr inhibitor
blocks the ability of MEKK1 [ mitogen activated protein kinase ( MAPK ) kinase kinase 1 ], an upstream kinase capable of stimulating the JNK ( c-Jun N-terminal protein kinase ) -c-Jun pathway, to induce apoptosis and activate
c-Jun
Levkovitz et al., J Neurosci 2002
:
A dominant negative Egr inhibitor blocks nerve growth factor induced neurite outgrowth by suppressing
c-Jun activation : role of an
Egr/c-Jun complex
Song et al., Neuroreport 2012
:
However, our data show that neither suppressing
Egr activity using a dominant negative mutant nor specifically silencing Egr-1 using small interfering RNA
inhibited the activation and expression of
c-Jun after activity deprivation in cerebellar granule neurons