Gene interactions and pathways from curated databases and text-mining

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INS — REG1A

Text-mined interactions from Literome

Marques et al., Diabetes Res Clin Pract 2000 (Diabetes Mellitus, Type 1...) : Insulin , at concentrations above physiological levels ( 1 mIU/ml ), inhibited the PTP activities in erythrocytes from normal subjects ( -15 +/- 4.1 %, P < 0.01 )
Kushner et al., Diabetes 2004 (Diabetes Mellitus, Type 1) : Protein tyrosine phosphatase-1b (Ptp1b) inhibits insulin and leptin signaling by dephosphorylating specific tyrosine residues in their activated receptor complexes
Benomar et al., Endocrinology 2009 : Interestingly, leptin as well as insulin induced the expression of phosphotyrosine phosphatase (PTP)-1B , whereas CNTF treatment did not affect its expression