Gene interactions and pathways from curated databases and text-mining

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DDIT3 — INS

Text-mined interactions from Literome

Oyadomari et al., J Clin Invest 2002 (Diabetes Mellitus, Type 2) : Overexpression of the mutant insulin in mouse MIN6 beta cells induced Chop expression and led to apoptosis
Araki et al., Experimental biology and medicine (Maywood, N.J.) 2003 (Diabetes Mellitus, Type 1...) : Overexpression of the mutant insulin in mouse MIN6 beta-cells induced CHOP expression and led to apoptosis
Miyata et al., Biochem Biophys Res Commun 2008 : Insulin induces chaperone and CHOP gene expressions in adipocytes
Du et al., Mol Endocrinol 2009 : In addition, we presented data to show that insulin , through a similar mechanism under which insulin induces TRB3 expression, promotes the expression of genes such as ANAS, ATF3, BIP, and CHOP , which are typical stress-responsive genes