◀ Back to INS
DDIT3 — INS
Text-mined interactions from Literome
Oyadomari et al., J Clin Invest 2002
(Diabetes Mellitus, Type 2) :
Overexpression of the mutant
insulin in mouse MIN6 beta cells
induced Chop expression and led to apoptosis
Araki et al., Experimental biology and medicine (Maywood, N.J.) 2003
(Diabetes Mellitus, Type 1...) :
Overexpression of the mutant
insulin in mouse MIN6 beta-cells
induced CHOP expression and led to apoptosis
Miyata et al., Biochem Biophys Res Commun 2008
:
Insulin induces chaperone and
CHOP gene expressions in adipocytes
Du et al., Mol Endocrinol 2009
:
In addition, we presented data to show that
insulin , through a similar mechanism under which insulin induces TRB3 expression,
promotes the expression of genes such as ANAS, ATF3, BIP, and
CHOP , which are typical stress-responsive genes