◀ Back to IL12RB2

IL10 — IL12RB2

Text-mined interactions from Literome

Zhang et al., J Interferon Cytokine Res 2000 : Corrective effects of interleukin-12 on age related deficiencies in IFN-gamma production and IL-12Rbeta2 expression in virus-specific CD8+ T cells
Reddy et al., Cell Immunol 2007 : CNTO 1275 inhibited upregulation of CLA, IL-12R , IL-2Ralpha and CD40L expression and also inhibited IL-12- and IL-23 induced IFN-gamma, IL-17A, tumor necrosis factor (TNF)-alpha, IL-2, and IL-10 secretion
Wu et al., Eur J Immunol 1997 : These results suggest that Th2 cell derived cytokines can inhibit IL-12 induced biological functions by inhibiting IL-12R expression and that expression of a second subunit of the IL-12R ( IL-12Rbeta2 ), required for the formation of high-affinity IL-12 binding sites, may be more highly regulated by TGF-beta2 and IL-10 than is expression of IL-12Rbeta1
Zhang et al., J Immunol 1999 (Tuberculosis) : In M. tuberculosis stimulated peripheral blood T cells from healthy tuberculin reactors, recombinant IL-10 and TGF-beta reduced IL-12R beta 1 and IL-12R beta 2 expression, as well as IFN-gamma production