◀ Back to IGF1
IGF1 — MEFV
Text-mined interactions from Literome
Belletti et al., Exp Cell Res 2002
:
The activated type 1
insulin-like growth factor ( IGF-IR )
increases the expression of Id1 proteins in
mouse embryo fibroblasts (MEF)
Butts et al., Horm Metab Res 2003
:
Furthermore,
IGF-I had no effect on the initial loss of
MEF2 transcriptional activity following hyperphosphorylation, but the recovery of MEF2 activity following restoration of intracellular calcium was significantly increased by IGF-I ... Furthermore, IGF-I had no effect on the initial loss of
MEF2 transcriptional activity following hyperphosphorylation, but the recovery of MEF2 activity following restoration of intracellular calcium was significantly
increased by
IGF-I
Wiedmann et al., J Neurosci Res 2005
(Second Messenger Systems) :
IGF-1 stimulated the gene transactivation activity of
MEF2 and its DNA binding potential
Muñoz et al., Biochem Biophys Res Commun 2009
(Cardiomegaly) :
IGF-1 stimulated
MEF2 dependent-gene transcription in a time dependent manner, as indicated by increased MEF2 promoter-driven reporter gene activity ; IGF-1 also induced p38-MAPK phosphorylation, while an inhibitor of p38-MAPK decreased both effects ... Additionally, inhibitors of phosphatidylinositol 3-kinase and calcineurin prevented
IGF-1 induced
MEF2 transcriptional activity