Gene interactions and pathways from curated databases and text-mining

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IGF1 — MEFV

Text-mined interactions from Literome

Belletti et al., Exp Cell Res 2002 : The activated type 1 insulin-like growth factor ( IGF-IR ) increases the expression of Id1 proteins in mouse embryo fibroblasts (MEF)
Butts et al., Horm Metab Res 2003 : Furthermore, IGF-I had no effect on the initial loss of MEF2 transcriptional activity following hyperphosphorylation, but the recovery of MEF2 activity following restoration of intracellular calcium was significantly increased by IGF-I ... Furthermore, IGF-I had no effect on the initial loss of MEF2 transcriptional activity following hyperphosphorylation, but the recovery of MEF2 activity following restoration of intracellular calcium was significantly increased by IGF-I
Wiedmann et al., J Neurosci Res 2005 (Second Messenger Systems) : IGF-1 stimulated the gene transactivation activity of MEF2 and its DNA binding potential
Muñoz et al., Biochem Biophys Res Commun 2009 (Cardiomegaly) : IGF-1 stimulated MEF2 dependent-gene transcription in a time dependent manner, as indicated by increased MEF2 promoter-driven reporter gene activity ; IGF-1 also induced p38-MAPK phosphorylation, while an inhibitor of p38-MAPK decreased both effects ... Additionally, inhibitors of phosphatidylinositol 3-kinase and calcineurin prevented IGF-1 induced MEF2 transcriptional activity