UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to FOXO4

FOXO4 — YWHAG

Pathways - manually collected, often from reviews:

NCI Pathway Database FoxO family signaling: FOXO4 (FOXO4) → FOXO4/14-3-3 family complex (FOXO4-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (translocation, collaborate)
Brownawell et al., Mol Cell Biol 2001
Evidence: mutant phenotype, physical interaction
NCI Pathway Database FoxO family signaling: Ran/GTP/Exportin 1 complex (RAN-XPO1) → FOXO4/14-3-3 family complex (FOXO4-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (translocation, activates)
Brownawell et al., Mol Cell Biol 2001
Evidence: mutant phenotype, physical interaction
NCI Pathway Database Class I PI3K signaling events mediated by Akt: FOXO1-3a-4/14-3-3 family complex (FOXO3_FOXO4_FOXO1-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) → 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) (modification, collaborate)
Brunet et al., Cell 1999, Kops et al., Nature 1999, Rena et al., J Biol Chem 1999, Brunet et al., J Cell Biol 2002
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Class I PI3K signaling events mediated by Akt: FOXO1-3a-4/14-3-3 family complex (FOXO3_FOXO4_FOXO1-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) → FOXO1-3a-4-inactive (FOXO3/FOXO4/FOXO1) (modification, collaborate)
Brunet et al., Cell 1999, Kops et al., Nature 1999, Rena et al., J Biol Chem 1999, Brunet et al., J Cell Biol 2002
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Class I PI3K signaling events mediated by Akt: 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) → FOXO1-3a-4-inactive (FOXO3/FOXO4/FOXO1) (modification, collaborate)
Brunet et al., Cell 1999, Kops et al., Nature 1999, Rena et al., J Biol Chem 1999, Brunet et al., J Cell Biol 2002
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FoxO family signaling: FOXO4 (FOXO4) → 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) (modification, collaborate)
Brownawell et al., Mol Cell Biol 2001
Evidence: physical interaction
NCI Pathway Database FoxO family signaling: FOXO4 (FOXO4) → FOXO4/14-3-3 family complex (FOXO4-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, collaborate)
Brownawell et al., Mol Cell Biol 2001
Evidence: physical interaction
NCI Pathway Database FoxO family signaling: 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) → FOXO4/14-3-3 family complex (FOXO4-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, collaborate)
Brownawell et al., Mol Cell Biol 2001
Evidence: physical interaction