Jiménez-Altayó et al., J Pharmacol Exp Ther 2006
:
IL-1beta impaired acetylcholine (ACh) and sodium nitroprusside ( SNP ) vasodilation and increased nitrite and O ( 2 ) (. ) production and inducible nitric-oxide synthase (iNOS), xanthine oxidase, and p22(phox) expression
Aubé et al., Gut 1996
:
Pretreatment with cycloheximide blocked IL 1 beta induced inhibition of ACh stimulated jejunal contraction, suggesting that a newly synthesised protein was involved in the effect